Lastly, clonidine enhances neuraxial opioids and, in combination with fentanyl, interacts in an additive manner, which can reduce the dose of each and every ingredient by 60% for postoperative analgesia. Extreme Allergic Reactions. Clonidine may perhaps bring about allergic reactions, which may be really serious. End using clonidine and https://jackc268ghc5.wikicorrespondent.com/user