Peginterferon alfa 2a will increase the level or influence of caffeine by influencing hepatic enzyme CYP1A2 metabolism. Slight/Importance Not known. lorlatinib will reduce the extent or effect of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Avoid utilization of lorlatinib with CYP3A substrates, where https://anatoleu197ajp9.blogars.com/profile